
Clinical Formulation Guide
The Art of
Formulation Layering
To achieve maximum efficacy from your KENTELLE formulations, products must be applied in harmony with their molecular weight, texture, and emulsion type. Layering incorrectly can create a barrier that prevents active ingredients from penetrating the skin.
The Golden Rule
Always layer from thinnest to thickest — water-based before oil-based.

Section 01
The 5 Rules of Texture Layering
Each texture type has a specific place in the layering sequence. Follow this order to ensure every active reaches its intended depth in the skin.
- 01
Water-Based Fluids & Serums
Thinnest — Apply FirstTexture: Aqueous, completely liquid, or lightweight gels.
The Science: These formulas contain low-molecular-weight actives (like Hyaluronic Acid, Vitamin C, or Peptides) designed to penetrate deeply and rapidly into the skin matrix.
Application Order: FIRST. Always apply these directly to clean, toned skin so nothing blocks their absorption.
- 02
Gels & Light Lotions
Second LayerTexture: Water-rich, oil-free, or very low-oil semi-solids that melt into the skin.
The Science: Designed to deliver intense hydration and targeted actives without adding heavy lipids.
Application Order: SECOND. These slip perfectly over fluids and provide a smooth, hydrating base.
- 03
Oil-in-Water (O/W) Emulsions
Most Creams & Day MoisturisersTexture: Classic, creamy textures that feel hydrating but absorb cleanly without a greasy residue.
The Science: Microscopic oil droplets are suspended inside a water base. The water evaporates or absorbs first, delivering hydration, while the light oils remain on the surface to lock it in.
Application Order: THIRD. These act as your daily hydrators, locking in your underlying fluids and gels.
- 04
Water-in-Oil (W/O) Emulsions
Rich Night Creams & Eye CreamsTexture: Dense, rich, and deeply emollient.
The Science: Tiny water droplets are trapped inside a rich oil base. This creates a powerful, slow-releasing protective barrier that prevents trans-epidermal water loss (TEWL).
Application Order: FOURTH. Because the outer layer is oil, water-based products cannot penetrate through it. This must go near the end of your routine to seal everything in.
- 05
Pure Oils & Occlusives
Thickest — Apply LastTexture: Liquid lipids or anhydrous (waterless) balms.
The Science: These do not hydrate the skin; instead, they act as an impenetrable atmospheric shield to trap all previous layers of moisture underneath.
Application Order: LAST. Oil repels water. If you apply a pure oil first, any serum you put on top will simply slide off.

Section 02
Routine Reference Guide
Your complete application sequence at a glance
| Step | Product Type | Emulsion / Texture | Core Purpose |
|---|---|---|---|
| 1 | Cleanse & Tone | Aqueous / Liquid | Prep and balance skin pH |
| 2 | Targeted Ampoules & Fluids | Water-Based Fluid | Deep active ingredient delivery |
| 3 | Hydrating Gels / Light Serums | Water-Gel | Surface plumping and hydration |
| 4 | Day Moisturisers / Lotions | Oil-in-Water (O/W) Cream | Nutrient delivery & light protection |
| 5 | Rich Treatment Creams | Water-in-Oil (W/O) Cream | Deep overnight barrier repair |
| 6 | Face Oils (If using) | Anhydrous Lipid | Final moisture lock |
Clinical Tip: The 60-Second Rule
Allow each layer to absorb for roughly 30–60 seconds before applying the next texture. This allows the emulsion to settle perfectly into the skin barrier, prevents your formulas from pilling on the surface, and maximises active ingredient delivery.

Section 03
Why Order Matters
The skin is a selective barrier. Molecule size and emulsion type determine how far an ingredient travels through the epidermis. Apply a heavy oil-based product first and you create a lipid barrier that physically blocks everything you apply after it.
Applying in the correct sequence — thinnest to thickest — ensures your actives reach the layers of skin where they are most effective, rather than sitting on the surface.
Section 04
Quick Layering Reference
- 1
Water-Based Serums & Fluids
Thinnest — apply first
- 2
Hydrating Gels & Light Serums
Water-gel textures
- 3
Day Moisturisers (O/W Creams)
Oil-in-water emulsions
- 4
Night Creams & Eye Creams (W/O)
Water-in-oil emulsions
- 5
Face Oils & Occlusives
Thickest — apply last

Layer With Intention
The right product applied in the wrong order is a wasted product. Follow the science, and let every layer work for you.